biomedical engineering
Optimization of Polycaprolactone Scaffold Fabrication for Tissue Engineered “Blood Vessel Mimics”
Through this SURP project, students used electrospinning techniques to optimize the production of a novel polymer scaffold used in tissue-engineered “blood vessel mimics” (BVMs). Each student investigated a separate solvent system to determine which would create the most reproducible and desirable results with the novel polymer. Results demonstrated that both scaffold fabrication procedures produced successful scaffolds for use in BVMs.
Evidation Health Project
The issue that Evidation Health brought to us with this project was a lack of standardization of patient-generated health data, (PGHD), which has significant impact on how effectively this form of data can be applied to formal research. As a company focused on analyzing PGHD in relation to personal health outcomes, Evidation Health great interest in developing standardized ways to collect, compile, and manipulate this data, especially between different sources. Thus, they tasked the team at Cal Poly with researching, developing, and documenting a software tool to help tackle this problem. From there, we set a goal to take data for a single domain from two different sources, aggregate the data together, and present a standardized dataset that showcases the specific data domain holistically. For this project we chose to focus on daily heart rate readings from Fitbit and Apple HealthKit devices. We were able to create a standardization method that consists primarily of using the Spark SQL module to manipulate data so that it conforms to a standardized Spark DataFrame. Ideally this will provide a basis for a more sophisticated, modular, and scalable standardization method which can be applied across multiple domains.
Learning to Denoise Low-Dose CT Scans
This SURP project explores the use of deep learning to denoise raw CT image data acquired at low-radiation dose. The goal is to recover clean CT images from noisy data that are comparable to CT scans imaged at full-radiation dose.